Siham Makhloufi

Co-Founder & CEO of I-Kare Vision, I lead healthcare innovation at the intersection of medicine and technology, with a strong focus on Artificial Intelligence (AI) and digital health transformation.

My mission is to accelerate patient access to impactful solutions by driving clinical adoption from concept to market. With over 15 years of experience across clinical practice, research, and leadership roles in the pharmaceutical industry, I bring deep expertise in Medical Affairs and Clinical R&D. I have contributed to global portfolio strategies, led Phase I–IV clinical trials and early access programs, and partnered with cross-functional international stakeholders.

Project: Early access studies in oncology Nivolumab (OPDIVO) in various types of cancer. Innovation in R&D (Artificial Intelligence, Digital innovation). Key achievements: Covering medical input for all studies with full medical compliance of protocols, eligibility, and follow-up . Raising 2 projects in innovative digital e-consent for vulnerable population.

Projects: Global Established Products including medical device (Synvisc-One in Atrthitis), Several therapeutic areas (Cardiology, Metabolic diseases, Neurology, Rheumatology, Dermatology, Oncology etc.) Key achievements: worldwide portfolio optimization of 52 products, including marketing and Labelling improvement through successful Health authorities interactions and global medical supervision of internal and external projects in local and global level.